Discover Grünenthal

2/25/2026

In their INN Proposed List 133 (Page 258), the World Health Organisation (WHO) proposed the International Non-proprietary Name (INN) ‘tegacorat’ for our investigational medicine GRM-01, a non-steroidal selective glucocorticoid receptor agonist and modulator (SEGRAM). We anticipate the inclusion in the INN Recommended List in March 2026.

The Grünenthal proprietary asset is an oral investigational medicine currently in development for the treatment of Duchenne muscular dystrophy (DMD). Prior to the proposal of the INN, the asset was referred to as GRM-01 and GRT6019 in company publications and literature.

Under their constitutional mandate to “develop, establish and promote international standards with respect to biological, pharmaceutical and similar products”, the WHO assigns INNs to facilitate the identification of pharmaceutical substances or active pharmaceutical ingredients. Each INN is a unique, globally recognised name and is public property. An INN is also known as a generic name.