Grünenthal is a global leader in pain management.

Grünenthal is a global leader in pain management and related diseases. As a science-based, privately-owned pharmaceutical company, we have a long track record of bringing innovative treatments and state-of-the-art technologies to patients worldwide. Our purpose is to change lives for the better, and innovation is our passion. We are focusing all our activities and efforts on working towards our vision of a world free of pain.

Our Vision: A World Free of Pain

Grünenthal Stories

NOP First-In-Human-Trial Announcement Grünenthal

First participants enrolled in Phase I NOP trial

Grünenthal announced that the first participants have been enrolled in a first-in-human Phase I clinical trial for a nociceptin (NOP) receptor agonist. The trial will include 90 healthy volunteers and aims to demonstrate a favourable safety and tolerability profile and to confirm the pharmacokinetic characteristics of the compound after single and multiple ascending doses. The results of the trial are expected in Q3 2025.
Get more insides in our Press Release
Grünenthal Annual Report 2023/24 (Grünenthal Scientific Body & Grünenthal Report Cover Image)

Annual Report 2023/24

4,400 Grünenthal employees worldwide join forces every day to drive progress towards our vision of a World Free of Pain. Together, we achieved record revenues in 2023. And our scientists made important progress with developing innovative medicines for pain patients.

Our most recent report shares information about our company’s strategy, highlight projects and financial performance.

Check out the Grünenthal Report.
Grünenthal Responsibility

Responsibility Report 2023

Grünenthal’s strategy and culture are closely tied to its deep commitment to conducting business responsibly. We aim to have a net-positive impact on patients, employees, partners, and wider society. Each year, we publish our progress in a detailed and externally audited report – in line with the Global Reporting Initiative (GRI) standards.
Check out our latest Responsibility Report.

The U.S. Food and Drug Administration (FDA) has granted breakthrough therapy designation to resiniferatoxin for pain associated with knee osteoarthritis (OA). The investigational, non-opioid medicine is currently in Phase III clinical development.

Knee OA affects more than 360 million people worldwide. Patients often experience severe pain, and many are impacted in their daily activities. If approved, resiniferatoxin could become a meaningful treatment option providing long-lasting pain relief and functional improvement of the affected joint.

Learn more about our asset and how it may address one of the most common and severe symptoms in knee OA

Download PR FDA Breakthrough Therapy Designation for Grünenthal’s resiniferatoxin
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Careers

Working at Grünenthal means experiencing the impact you can have on the results we achieve and the lives of the patients we serve.

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Innovate for a world free of pain.


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